Any group can join CIMBA if they can submit a minimum of 50 female or 20 male mutation carriers, preferably with germline DNA samples available, who meet the criteria below.

If you are interested in participating in CIMBA, please visit the Contact page.

All carriers being submitted must:

• carry a pathogenic BRCA1 or BRCA2 mutation – more info at Mutation Classification Guidelines

• be >= 18 years of age at time of baseline interview
• have basic phenotype data available – more info at Phenotypic and Epidemiological data fields

These can be:

• 50 or more female affected or unaffected BRCA1/2 carriers who meet any of the following criteria:
  • have DNA sample available
  • have pathology data available
  • have clinical follow up data

Or:

• 5 males affected with breast or prostate cancer and 15 age-matched (within 5 years) carrier controls, all preferably with germline DNA samples

The additional CIMBA data dictionaries can be viewed here

If you are interested in participating in CIMBA, please complete the CIMBA application form.